Lyme disease is caused by the bacterium Borrelia burgdorferi.
It is transmitted to humans by the bite of infected black-legged ticks. Symptoms may include fever, headache, fatigue, and a characteristic skin rash called erythema migrans.
If left untreated, an infection can spread to joints, the heart, and the nervous system. Lyme disease is diagnosed based on symptoms, physical findings (e.g., rash), and the possibility of exposure to infected ticks; laboratory testing is helpful in the later stages of a disease.
The diagnosis of Lyme disease is most often made by clinical examination combined with evidence of tick bite or exposure in endemic areas. Amplification of Borrelia genomic DNA from blood, fluids or tissues can support the diagnosis. Because of the sensitivity of the PCR test, the infection can be exposed more quickly than using an antibody test. This qualitative test will show positive or negative results.
The Lyme Disease Antibodies Blood Test, IgG, and IgM, Immunoblot is a common test for Lyme Disease.