This test should NOT be performed on individuals with kidney disorders. Abnormal kidney function or use of diuretics may influence test results. Synthetic hormones will not show up on the test and conjugated equine estrogens will show up mostly as estrone.
The FMV is a single urine collection upon waking. It provides a time-average for hormone spikes that may occur during the hours of sleep (approximately 8-hours) and includes the early morning peak excretion expected in a number of hormones. As a result, the time-average of the overnight collection paired with capturing the peak excretion provides an estimate of both the Total Output and Peak Output of measured hormones.
The Complete Hormones provides insight into the contribution that sex hormones may have in patients presenting with hormone-related complaints, and helps assess disease risk associated with elevated estrogen metabolites.
Urine measures the most metabolites, providing more insight into associated disease risk.
The Complete Hormones profile evaluates:
- Progesterone (via pregnanediol)
- Glucocorticoids, including cortisol
- Androgens, including DHEA and testosterone, and their metabolites
- Estrogens (E1 Estrone, E2 Estradiol, E3 Estriol) and metabolites, including hydroxylated and methoxylated estrogens
- Methylation capacity
- 5α-reductase activity
- Anabolic/Catabolic Balance
When should the Complete Hormones test be considered?
The Complete Hormones test is designed to assist in the management of hormone-related symptoms in both males and females.
The Complete Hormones test is ideal for establishing a baseline assessment of parent hormones and their metabolites ahead of clinical intervention with hormone therapy (HT) as well as subsequent monitoring if needed in both female and male patients.
The Complete Hormones test provides insight into the impact that shifting hormone levels may play in men (andropause or male menopause) and women (peri/menopause). Symptoms include the following:
- Weight gain
- Muscle mass loss
- Muscle weakness
- Low libido and sexual performance issues
- Hair loss
- Sleep disturbances
- Brain fog
- Mood instability
- Hot flashes
- Vaginal dryness
In addition to supporting patient management around hormone-dependent symptoms, the profile provides valuable insight into disease risk for hormone-associated cancers (breast, prostate) and osteoporosis.